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Pharmaceutical trials

Posted By David L. Evans, Friday, December 20, 2013
Updated: Wednesday, April 16, 2014

New in the pharmaceutical world: April 10-17
Bad drug?
What is in that nutritional supplement you take?

http://blogs.scientificamerican.com/observations/2014/04/02/toxins-in-nutrition-supplements-still-escape-fda-oversight/

Complete, free blog from
Sci. Am.

Your brain on pot

http://healthyliving.msn.com/health-wellness/study-finds-signs-of-brain-changes-in-pot-smokers

Full, free report from
MSN

How effective is that anti-flu drug?


http://www.dddmag.com/news/2014/04/have-millions-been-wasted-flu-drug?et_cid=3875801&et_rid=54713780&type=headline

Full, free story from Drug discov. & develop.

NSAID's and atrial fibrillation


http://bmjopen.bmj.com/content/4/4/e004059.full

Full, free article, tables, linked citations from BMJ Open

The truth about coffee

Caffeine
v Alzheimer's tau deposits

http://www.biosciencetechnology.com/news/2014/04/caffeine-can-target-tau-deposits-alzheimers?et_cid=3868997&et_rid=54713780&location=top

Complete, free story from Biosci. Tech.

Coffee myths

http://www.nbcnews.com/feature/debunker/perk-evils-coffee-debunked-n17426

Full, free debunking video from MSN

Good drug

Green tea for the brain?

http://www.biosciencetechnology.com/news/2014/04/green-tea-boosts-your-brain?et_cid=3871407&et_rid=54713780&location=top

Full, free essay from Biosci. Tech.

Georgia governor OK's marijuana trials

http://www.dddmag.com/news/2014/04/governor-backs-medical-marijuana-trials?et_cid=3878080&et_rid=54713780&type=headline

Full, free item from Drug discov. & develop.

Your daily drug discoveries: April 3-10
Toxins in that supplement

http://blogs.scientificamerican.com/observations/2014/04/02/toxins-in-nutrition-supplements-still-escape-fda-oversight/

Complete, free story, links from Sci. Am.

Does vitamin D really reduce mortality?


http://www.bmj.com/content/348/bmj.g2035

Full, free article, graphics, linked citations from BMJ

Immunotherapy for allergies

http://www.dddmag.com/news/2014/04/fda-approves-first-hay-fever-immunotherapy-tablet?et_cid=3860244&et_rid=54713780&type=headline

Short, free item from Drug discov. & develop.

Want information on the new inhalable insulin?

http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM390865.pdf

From the manufacturer

Down on the pharm: March 27-April 3
Product tampering and recall: Alli

http://www.dddmag.com/news/2014/03/tampering-forces-massive-alli-recall?et_cid=3848351&et_rid=54713780&type=headline

Complete, free item from
Drug discov. & develop.

How does aspirin affect mortality in non-surgical cardiac work?

http://www.nejm.org/doi/full/10.1056/NEJMoa1401105?query=OF#t=articleTop

Short, free article, tables, linked citations from New Engl. j. Med.

E-cigarettes not helpful in quitting


http://www.scientificamerican.com/article/electronic-cigarettes-dont-aid-quitting/?&WT.mc_id=SA_DD_20140326

Full, free essay from Sci. Am.

Daily dose of drug data: March 20-27

Fluid for e-cigarettes potentially lethal

http://healthyliving.msn.com/health-wellness/nicotine-e-liquids-a-serious-health-threat-experts

Complete, free item, video from MSN

How does personalized medicine work?

http://www.dddmag.com/videos/2014/03/how-personalized-medicine-works-bananas-and-biomarkers?et_cid=3834351&et_rid=54713780&type=headline

Short note, video from Drug discov. & develop.

Anesthesia's darker side

http://www.scientificamerican.com/article/hidden-dangers-of-going-under/?&WT.mc_id=SA_MB_20140319

Full, free essay from Sci. Am.
.
Down on the pharm: March 13-20
Cut me off a chunk of that: chocolate pills!

http://www.dddmag.com/news/2014/03/chocolate-pills-be-tested-heart-health?et_cid=3828328&et_rid=54713780&type=headline

Full, free article from Drug discov. & devel.

Lethal injections delayed: no chemicals available

http://www.nbcnews.com/news/us-news/oklahoma-executions-delayed-amid-drug-shortage-n55926

Full, free story from NBC News


Drugs this week: March 6-13
Thanks this week to Tom Lehman
Altitude sickness and viagra

http://www.webmd.com/men/news/20050201/viagra-may-help-severe-altitude-sickness

Short, free item from WebMD

Pregnant, want to stop smoking? Maybe patches not so useful

http://www.bmj.com/content/348/bmj.g1622

Complete, free article, linked citations, graphics from BMJ

Culture dish hair follicle for drug testing

http://www.scientificamerican.com/article/hair-follicles-dish-make-cruelty-free-testing/?&WT.mc_id=SA_DD_20140311

Free book review from Sci. Am.

Generic lipitor recall

http://www.reuters.com/article/2014/03/08/us-ranbaxylab-lipitor-usa-recall-idUSBREA2703420140308?feedType=RSS&feedName=healthNews

Full, free story from
Reuters
.

Down on the pharm: Feb. 27-March 6

Good drugs


Female fertility and testosterone

http://www.biosciencetechnology.com/news/2014/03/female-fertility-what%E2%80%99s-testosterone-got-do-it?et_cid=3805205&et_rid=54713780&location=top#.UxeNa9JdXzg

Full, free essay from Biosci. Tech.

New drug for disease of little fat

http://www.dddmag.com/news/2014/02/fda-approves-bms-drug-rare-fat-disorder?et_cid=3789530&et_rid=54713780&type=headline

Short, free note from Drug discov. & develop.

What should the nation decide about the heroin overdose antidote?


http://www.dddmag.com/news/2014/02/heroin-overdose-antidote-sparks-debate?et_cid=3793989&et_rid=54713780&type=headline

Full, free essay from Drug discov. & develop.

Are those new diabetes drugs better?

http://www.dddmag.com/news/2014/03/new-diabetes-drugs-cost-more-may-not-work-better?et_cid=3799461&et_rid=54713780&type=headline

Full, free item from Drug discov. & develop.

Testing

Two diabetes drugs found safe to pancreas


http://www.nejm.org/doi/full/10.1056/NEJMp1314078

Complete, free prospective item from New Engl. j. Med.

Biowarfare program at Dachau

http://blogs.scientificamerican.com/talking-back/2014/02/21/the-nazis-biowarfare-program-at-dachau/

Complete, free story, links from Sci. Am.

Pharmaceutical news this week: Feb. 20-27

Weed

This marijuana strain can help children with a seizure disorder

http://www.dddmag.com/news/2014/02/special-marijuana-strain-aids-kids-seizures?et_cid=3776452&et_rid=54713780&type=headline

Full, free essay from Drug discov. & develop.

Can cannabis kill?

http://www.newscientist.com/article/dn25092

Full free story, link to research abstract from New Sci.

Other drugs

"Black box" warning urged for testosterone: MI risk

http://www.dddmag.com/news/2014/02/group-wants-heart-attack-warning-testosterone?et_cid=3788882&et_rid=54713780&location=top

Full, free essay from Drug discov. & develop.

Vitamin and mineral supplements v cardiovascular risk: nope

http://annals.org/article.aspx?articleid=1832969

Full, free article, graphics, linked citations from Ann. Int. Med.

Placental growth factor speeds healing

http://www.livescience.com/43548-engineered-growth-factor-helps-wounds-heal.html

Complete, free item, link from LiveScience

Your daily dose of drug news: Feb. 13-20

How many doses of HPV vaccine to protect against genital warts?

http://jama.jamanetwork.com/article.aspx?articleid=1829685

Full, free article, linked citations, graphics from JAMA

FDA looking into heart failure and saxagliptin, Type II diabetes drug

http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm385471.htm

FDA website

What's new in drugs: Feb. 6-13

Safety

Preventing liver damage from acetaminophen

http://www.dddmag.com/news/2014/02/preventing-liver-failure-painkiller-overdose?et_cid=3751573&et_rid=54713780&type=headline

Full, free item Drug discov. & develop.

Big pharma helping Olympic drug testing

http://www.biosciencetechnology.com/news/2014/02/pharma-data-play-larger-role-olympic-drug-tests?et_cid=3761042&et_rid=54713780&location=top#.UvqM5dJdXzg

Complete, free essay from Biosci. Tech.

Looking again at the heart safety of NSAIDs

http://www.dddmag.com/news/2014/02/fda-reconsiders-heart-safety-nsaids?et_cid=3761080&et_rid=54713780&location=top

Full, free piece from Drug discov. & develop.

On the cutting edge

Angiotensin II blocker successful against post-herpes pain

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(13)62337-5/abstract

Free abstract from Lancet

New antibody blocks factor XII

http://consumer.healthday.com/circulatory-system-information-7/clots-health-news-731/safer-blood-thinner-shows-promise-in-animals-684572.html

Complete, free essay from HealthDay News 

A new class of cholesterol drugs?

http://www.genengnews.com/gen-news-highlights/the-next-new-thing-in-curbing-cholesterol-may-be-sortilin/81249471/

Short, free piece from GEN

Phrom the pharm: Jan. 30-Feb. 6

Drugs and the law

Criminals in the pharma

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)60139-2/fulltext?elsca1=ETOC-LANCET&elsca2=email&elsca3=E24A35F

Full, free review from Lancet

Unauthorized HIV trial: leader fined

http://www.the-scientist.com//?articles.view/articleNo/39067/title/Unauthorized-HIV-Trial-Leader-Fined/

Short, free story, image, links from The Scientist

Today's drug news

Reversing fatty acid liver disease in mice

http://www.biosciencetechnology.com/videos/2014/02/obesity-induced-fatty-liver-disease-reversed-mice?et_cid=3747106&et_rid=54713780&type=headline#.UvEwYNJdXzg

Full, free essay from Biosci. Tech.

Trying to make a nonaddictive opioid

http://www.the-scientist.com/?articles.view/articleNo/38989/title/Pain-and-Progress/

Complete, free article, image from The Scientist

Sublingual tablet for ragweed allergy

http://www.dddmag.com/news/2014/01/fda-committee-recommends-ragweed-therapy-approval?et_cid=3738929&et_rid=54713780&location=top

Short, free item from Drug discov. & develop.

Tobacco: more deadly to Americans than WWII

http://www.lung.org/associations/states/colorado/tobacco/

From the Am. Lung Assoc.

Better drugs now: Jan. 23-30

Postmenopausal estrogen supplements and pancreatitis

http://www.cmaj.ca/content/early/2014/01/27/cmaj.131064.full.pdf+html

Full, free article, graphics, references from CMAJ

Reducing unnecessary prescriptions for drugs

http://blogs.scientificamerican.com/observations/2014/01/27/a-simple-way-to-slash-unnecessary-drug-prescriptions/

Full, free blog, links from Sci. Am.

Fish omega-3 oils and brain cells

http://www.biosciencetechnology.com/news/2014/01/can-fish-oil-preserve-brain-cells?et_cid=3728493&et_rid=54713780&type=headline#.UuKKbdIo5pg

Complete, free essay from Biosci. Tech.

Are ketone-based drinks in the future for athletes?

http://www.scientificamerican.com/video/ketone-based-sports-drink-promises-edge-for-athletes/?&WT.mc_id=SA_DD_20140122

Brief, free note, video from Sci. Am.

Your daily dose of drugs: Jan. 16-23

Drugs today!

Trying to overcome the blood brain barrier for drug delivery

http://blogs.scientificamerican.com/talking-back/2014/01/12/fooling-brain-defenses-to-deliver-an-alzheimers-drug/?WT_mc_id=SA_CAT_MB_20140115

Complete, free blog from Sci. Am.

Diabetes type II prevention with food

http://www.dddmag.com/news/2014/01/compounds-chocolate-tea-berries-could-guard-against-diabetes?et_cid=3721414&et_rid=54713780&location=top

Full, free item from Drug discov. & develop.

Tradition Chinese medicines getting new look

http://www.dddmag.com/articles/2014/01/turning-ancient-chinese-meds-modern-drugs?et_cid=3714687&et_rid=54713780&type=headline

Full, free essay from Drug discov. & develop.

Herbal medicine combo. delays progression to diabetes

http://press.endocrine.org/doi/abs/10.1210/jc.2013-3276

Free summary from J. clin. endocrin. metabol.

Not all drug approvals equal

http://www.dddmag.com/news/2014/01/all-fda-drug-approvals-not-created-equal?et_cid=3726349&et_rid=54713780&type=headline

Short, free item from Drug discov. & develop.

NSAID's

Fever-reducing drugs could make flu worse, more deaths

http://www.dddmag.com/news/2014/01/fever-reducing-drugs-may-help-spread-flu?et_cid=3726349&et_rid=54713780&location=top

Complete, free essay from Drug discov. & develop.

Warning about high doses of acetominophen

http://www.dddmag.com/news/2014/01/fda-warns-against-high-dose-acetaminophen?et_cid=3712933&et_rid=54713780&type=headline

Full, free item from Drug discov. & develop.

What's new on the pharm: Jan. 9-16

Why new drug development is so hard

http://blogs.scientificamerican.com/the-curious-wavefunction/2014/01/10/why-drug-discovery-is-hard-part-3-vacuum-cleaners-that-make-sir-james-weep/?WT_mc_id=SA_DD_20140110

Complete, free blog, images, links from Sci. Am.

FDA issues safety alert for sodium phosphate supplements

http://www.nsf.gov/news/special_reports/winterolympics/injury.jsp

From the website

Phancy pharmacy: Jan 2-9

Good drug

Getting antibodies across the blood-brain barrier

http://www.dddmag.com/news/2014/01/new-method-transports-antibodies-across-blood-brain-barrier?et_cid=3699364&et_rid=54713780&location=top

Full, free story from Drug discov. & develop.

Compound from roots of flower show anti-inflammatory promise

http://www.rdmag.com/news/2014/01/chinese-herbal-compound-relieves-inflammatory-neuropathic-pain?et_cid=3691701&et_rid=54713780&location=top

Full, free essay from R&D Mag..

Bad drug

Allegation: woman died from alternative cancer therapy

http://www.scientificamerican.com/article.cfm?id=womans-death-linked-to-alternative-medicine

Complete, free article, links from Sci. Am..

Why drugs cost so darned much

http://blogs.scientificamerican.com/the-curious-wavefunction/2014/01/06/why-drugs-are-expensive-its-the-science-stupid/?WT_mc_id=SA_DD_20140106

Full, free blog, image, link, references from Sci. Am..

Your daily dose of drugs: Dec. 26-Jan 2

Vitamin E supplements v Alzheimer Disease progression

http://jama.jamanetwork.com/article.aspx?articleid=1810379

Free abstract from JAMA..

What about the Drug Quality and Security Act?

http://www.nejm.org/doi/full/10.1056/NEJMp1314691?query=TOC

Full, free perspective item, linked citations, table from New Engl. j. Med.

Down on the pharm: Dec. 19-26

Better drug

Cure for HIV still a long ways off?

http://www.rdmag.com/articles/2013/12/distant-hope?et_cid=3666083&et_rid=54713780&location=top

Complete, free essay, image from R&D Mag.

Work toward an insulin pill

http://www.dddmag.com/news/2013/12/new-developments-toward-insulin-pill-reported?et_cid=3666161&et_rid=54713780&location=top

Full, free item from Drug discov. & develop.

Bad drug 

One lot of HPV vaccine recalled

http://www.cdc.gov/media/releases/2013/s1220-gardasil-vaccine.html

Free piece from MMWR

Increased use of dietary supplements and rise in liver dysfunction

http://www.nytimes.com/2013/12/22/us/spike-in-harm-to-liver-is-tied-to-dietary-aids.html?_r=0

Newspaper article

Drugs this week: Dec. 12-19

Diabetes

Diabetes drug affects men's/women's hearts differently

http://www.dddmag.com/news/2013/12/diabetes-drugs-affect-hearts-men-women-differently?et_cid=3654715&et_rid=54713780&location=top

Full, free essay from Drug discov. & develop.

Statins, diuretics increase risk of diabetes in glucose--intolerance

http://www.bmj.com/content/347/bmj.f6745

Full, free article, video abstract, graphics, linked citations from BMJ

Other conditions

Greater chance of B-12 deficiency with long-term proton pump use

 http://jama.jamanetwork.com/article.aspx?articleid=1788456

Free abstract from JAMA

How Ms. Mosquito finds you: ways to thwart?

 https://ucrtoday.ucr.edu/19377

Press release, video, links from US/Riverside


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