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Pharmaceutical trials

Posted By David L. Evans, Friday, December 20, 2013
Updated: 11 hours ago
Important pharmaceutical news: July 24-31
Tuskegee experiment revealed--July 29, 1972

http://blogs.scientificamerican.com/urban-scientist/2014/07/28/you-should-know-july-29-1972-important-date-in-bioethics-science-and-black-history/

​Complete, free blog, links, images from
Sci. Am.

Ecstasy abuse and spinal artery aneurysm

http://casereports.bmj.com/content/2014/bcr-2014-011248?etoc

​Short, free note from BMJ Case Rep.

Drugs today: July 17-24
More teenagers using human growth hormone now

http://www.dddmag.com/news/2014/07/survey-finds-sharp-increase-teen-hgh-use?et_cid=4062456&et_rid=54713780&location=top

Full, free story, graphs from
Drug discov. & develop.

Does the pharm affect sexual behavior?

http://www.the-scientist.com//?articles.view/articleNo/40305/title/Sex-and-Drugs/

Full, free report, links from
The Scientist

Niacin safe and effective? Nope

http://www.nejm.org/doi/full/10.1056/NEJMoa1300955?query=TOC

Complete, free article from
New Engl. j. Med.

​Worldwide trials of fetal stem cells for parkinsonism

http://www.biosciencetechnology.com/articles/2014/07/long-awaited-global-trial-fetal-cells-parkinson%E2%80%99s?et_cid=4058451&et_rid=54713780&type=headline

Full, free story, links from Biosci. Tech.

Warning about caffeine powder

http://www.fda.gov/Food/RecallsOutbreaksEmergencies/SafetyAlertsAdvisories/ucm405787.htm

Press release from FDA

The phamily pharm: July 10-17
Thanks to 'net detectives Paul Blumstein and Henriette Evans

Drugs from here and there

Do emergency contraceptives cause abortions?


http://www.scientificamerican.com/article/fact-or-fiction-emergency-contraceptives-cause-abortions/?&WT.mc_id=SA_HLTH_20140708

Complete, free essay from
Sci. Am.

New approaches to jet lag medicine on the horizon

http://www.scientificamerican.com/article/new-drug-targets-promise-to-treat-jet-lag/?&WT.mc_id=SA_DD_20140714

Full, free essay, link from
Sci. Am.

Drug candidate for sickle cell disease

http://www.nih.gov/news/health/jul2014/ncats-09.htm

Press release from NIH

Nice drugs--maybe

Electrical pot?


http://www.scientificamerican.com/article/new-electronic-joint-ignites-e-device-debate/?&WT.mc_id=SA_HLTH_20140708

Full, free report, link from
Sci. Am.

A drug addressing low sexual desire in women

http://www.the-scientist.com//?articles.view/articleNo/40272/title/That-Loving-Feeling/

Complete, free article, links, references from
The Scientist

Chocolate ingredient hardens tooth enamel

http://cosmeticdentistry.about.com/od/Dental-Health/fl/Is-Chocolate-Good-for-Your-Smile.htm

Website, further links

Drugs today: July 3-10
Can medical research with prisoners be justified?

http://www.scientificamerican.com/article/should-prisoners-be-used-in-medical-experiments/?&WT.mc_id=SA_HLTH_20140708

Full, free article, links from
Sci. Am.

Only 1% of Alzheimer Disease drugs succeed in clinical trials

http://www.dddmag.com/news/2014/07/99-alzheimers-drug-trials-fail-study-says?et_cid=4034980&et_rid=54713780&type=headline

Complete, free report from
Drug discov. & develop.

Forget the vitamin pills, look for the new bananas!

http://www.scientificamerican.com/article/super-bananas-enter-u-s-market-trials/?&WT.mc_id=SA_EVO_20140707

Full, free essay from
Sci. Am.

Why some pediatricians stop giving vaccines

http://www.nytimes.com/2014/07/03/health/Vaccine-Costs-Soaring-Paying-Till-It-Hurts.html?_r=1

Newspaper story

Phun on the pharm: June 26-July 3

ADHD drugs apparently do not increase suicide risk

http://www.bmj.com/content/348/bmj.g3769

Full, free article, graphics, linked citations from BMJ

FDA requiring label change on testosterone: warning on VTE

http://www.fda.gov/Drugs/DrugSafety/ucm401746.htm

Press release from FDA

Down on the pharm: June 19-June 26

Just how useful are dietary supplements?

http://www.scientificamerican.com/article/health-impact-of-vitamin-pills-remains-uncertain-in-developed-world/?&WT.mc_id=SA_DD_20140627

Full, free story, link from
Sci. Am.

Glargine: biosimilar for insulin approved in Europe

http://www.dddmag.com/news/2014/06/lilly-bi-compound-first-biosimilar-insulin-backed-chmp?et_cid=4019288&et_rid=54713780&type=headline

Complete, free essay from
Drug discov. & develop.

Anti-virals for polio?

http://www.the-scientist.com//?articles.view/articleNo/40244/title/To-Finish-Off-Polio/

Full, free article, links from
The Scientist
What the pharma has today: June 12-19

HIV treatment: curing babies?

http://www.scientificamerican.com/article/hiv-on-trial-an-attempt-to-cure-the-world-s-smallest-patients/?&WT.mc_id=SA_DD_20140616

Full, free story from Sci. Am.

Molecular profiling for more efficient clinical trials

http://www.scientificamerican.com/article/clinical-trials-more-trials-fewer-tribulations/?&WT.mc_id=SA_HLTH_20140617

Full, free essay from
Sci. Am.

Will this help in human ALS?


http://www.dddmag.com/news/2014/06/copper-compound-ups-lifespan-mice-als?et_cid=3994102&et_rid=54713780&type=headline

Complete, free report from Drug discov. & develop.

Drug news of the day: June 5-12

Thanks this week to 'net detective Paul Blumstein
Cannabis corner

What's wrong with pot?

http://www.biosciencetechnology.com/news/2014/06/review-summarizes-research-marijuana%E2%80%99s-negative-health-effects?et_cid=3981724&et_rid=54713780&location=top

Complete free essay on negative affects from Biosci. Tech.


Cannabis, other factors affect size, shape of sperm


http://www.biosciencetechnology.com/news/2014/06/sperm-size-shape-affected-cannabis-use?et_cid=3979558&et_rid=54713780&location=top

Full, free report from
Biosci. Tech.

Troubled pharma

"Fight the fakes" campaign combats phony meds

http://www.dddmag.com/news/2014/06/fight-fakes-campaign-gains-new-partners?et_cid=3981082&et_rid=54713780&location=top

Complete, free essay from Drug discov. & develop.

Arrested: drug researcher's drug data allegedly inflated

http://www.dddmag.com/news/2014/06/ex-novartis-employee-arrested-over-drug-data?et_cid=3989314&et_rid=54713780&location=top

Full, free report from
Drug discov. & develop.

Your daily dose of drug discoveries

Need help with a hangover?


http://www.wired.com/2014/05/hangover-cure/?mbid=nl_wired_06102014

Full, free story from
Wired

Spot test for presence of drug in blood stream


http://www.newsdaily.com/health/7d1bad70c78f4dcf6adc1d324e2f9aa4/colour-changing-molecule-can-monitor-drug-dosages

Full, free item, images from Agence France Press

Artificial blood design

http://www.medicaldaily.com/blood-transfusion-using-one-size-fits-all-artificial-blood-could-revolutionize-reach-and-shelf-life

Full, free story, links from
MedicalDaily

Drugs in the diet

Lycopene extracted from tomatoes increases cardiovascular function


http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0099070

Full, free article, linked citations, graphics from
PLoS One

Green tea increases DNA repair activity

http://www.the-scientist.com//?articles.view/articleNo/40061/title/Beneficial-Brew/

Complete, free review item, link to original abstract from The Scientist


Deadly diet-drug duos!


https://shine.yahoo.com/healthy-living/7-most-dangerous-drug-food-combinations-152100149.html

Free website from Yahoo!

Advertising drugs

Are opioid ads contributing to abuse epidemic in Chicago?


http://www.genengnews.com/gen-news-highlights/chicago-sues-five-opioid-makers-linking-abuse-to-marketing/81249950/

Complete, free essay from
GEN

Drug ads directed to consumers: often emotional appeals


http://www.oncologynurseadvisor.com/direct-to-consumer-cancer-center-ads-emphasize-emotion-over-info/article/349177/?DCMP=EMC-ONA_EditorsChoice&spMailingID=8741950&spUserID=NTQ2MjY4MDk2ODIS1&spJobID=320448648&spReportId=MzIwNDQ4NjQ4S0

Short, free item from Oncol. Nurse Advis.

What's new at the pharma: May 29-June 5

Drug testing



New York to begin clinical trials on cannabidiol from marijuana

http://www.dddmag.com/news/2014/06/new-york-hold-clinical-trials-marijuana?et_cid=3976437&et_rid=54713780&type=headline


Complete, free item from Drug discov. & develop.


Big pharma opens up many clinical trial data

http://www.scientificamerican.com/article/secret-clinical-trial-data-to-go-public/?&WT.mc_id=SA_DD_20140603

Full, free article from
Sci. Am.

Longer prostate cancer survivorship with an old approach

http://www.dddmag.com/news/2014/06/cheap-drug-greatly-boosts-prostate-cancer-survival?et_cid=3974269&et_rid=54713780&location=top

Complete, free item, image from
Drug discov. & develop.


Successful therapies

An alternative to estrogen for hot flashes


http://archinte.jamanetwork.com/article.aspx?articleid=1876676



Free abstract from
JAMA Int. Med.

Capsaicin blocks pain receptors, extends lifespan in mice

http://www.dddmag.com/news/2014/05/pain-killers-improve-metabolic-health-and-longevity?et_cid=3957453&et_rid=54713780&type=headline

Full, free report from Drug discov. & develop.


Daily drug discoveries: May 22-29


NIH no longer requiring special reviews of gene therapy trials

http://news.sciencemag.org/biology/2014/05/nih-will-no-longer-require-special-review-u.s.-gene-therapy-trials

Short, free report from
Science

Advantame: the newly-approved sugar substitute


http://www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm397740.htm

Press release from FDA


Red wine: the anti-cavity drink
http://www.acs.org/content/acs/en/pressroom/presspacs/2014/acs-presspac-may-21-2014/red-wine-shows-promise-as-cavity-fighter.html

Press release from Am. Chem. Soc.


The newest in drug discoveries: May 15-22


Some good news

A shot of caffeine for that preemie's respiration?


http://www.biosciencetechnology.com/news/2014/05/caffeine-helps-premature-babies-breathe-easier?et_cid=3942565&et_rid=54713780&location=top

Full, free report from
Biosci. Tech.

Could this lipid help in sickle cell anemia?

http://bionews-tx.com/news/2014/05/19/uthscs-biochemists-reduce-sickling-and-progression-of-sickle-cell-disease-in-mice-using-s1p/#respond

Full, free essay from
BioNews Texas

Vitamin C alleviates some fetal effects from smoking mom

http://www.scientificamerican.com/podcast/episode/vitamin-c-helps-fetus-in-smoking-moms/?&WT.mc_id=SA_DD_20140521

Free audio file from Sci. Am.

The immune system and drugs

Delayed MMR vaccination to two years old, seizures more likely


http://pediatrics.aappublications.org/content/early/2014/05/14/peds.2013-3429.full.pdf+html

Full, free article, graphics, references from
Pediatrics

Shark antibodies hold promise in human therapy

http://blogs.scientificamerican.com/observations/2014/05/18/using-sharklike-antibodies-to-fight-disease/

Complete, free blog, link from Sci. Am.

Down on the pharm: May 8-15

New from the pharma

What is inside the e-cigarette smoke?


http://www.biosciencetechnology.com/news/2014/05/e-cigarettes-expose-people-more-%E2%80%98harmless%E2%80%99-water-vapor?et_cid=3940395&et_rid=54713780&location=top

Complete, free essay from
Biosci. Tech.

Soy sauce molecule to fight HIV?


http://www.bioresearchonline.com/doc/soy-sauce-molecule-may-unlock-drug-therapy-for-hiv-0001

Short, free note, link from
Bioresearch Online

Those mushrooms take care of the negativity

http://www.biosciencetechnology.com/news/2014/05/psilocybin-inhibits-processing-negative-emotions-brain?et_cid=3927190&et_rid=54713780&location=top

Full, free report, image from
Biosci. Tech.

New type of anticoagulant prevents platelet clumping

http://www.dddmag.com/news/2014/05/fda-approves-merck-blood-thinner-some-patients?et_cid=3931114&et_rid=54713780&location=top

Full, free item from
Drug discov. & develop.

Surprises from older drugs

Antidepressant cuts plaques growth in Alzheimer Disease by 78%

http://www.biosciencetechnology.com/articles/2014/05/anti-depressant-reduces-alzheimer%E2%80%99s-plaque-growth-78-percent?et_cid=3940395&et_rid=54713780&type=headline

Full, free essay, image from
Biosci. Tech.

Erectile dysfunction drugs raises blood flow to muscles in Duchenne Muscular Dystrophy


http://www.dddmag.com/news/2014/05/tadalafil-sildenafil-promising-duchenne-muscular-dystrophy?et_cid=3929383&et_rid=54713780&type=headline

Complete, free essay from Drug discov. & develop.


Drug news: May 1-8

Important news: Aspirin no longer recommended for MI prevention

http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm390574.htm

Press release from FDA


What ELSE does that drug do!


http://blogs.scientificamerican.com/observations/2014/05/02/the-quest-how-to-research-pharmaceutical-drugs/

Full, free article, links from
Sci. Am.

Lethal drugs for legal executions

http://www.scientificamerican.com/article/lete28099s-stop-pretending-the-death-penalty-is-a-medical-procedure-editorial/?&WT.mc_id=SA_MB_20140430

Full, free editorial from
Sci. Am.

Discovery of new drugs: April 24-May 1

Psychoactive drugs


Cannabis use and risk of cardiovascular diseases


http://jaha.ahajournals.org/content/3/2/e000638.full

Full, free article, tables, linked citations from
J. Am. Heart Assoc.

The ban on research into psychoactive drugs


http://www.scientificamerican.com/article/end-the-ban-on-psychoactive-drug-research/?&WT.mc_id=SA_DD_20140207

Complete, free report from
Sci. Am.

Good drug

Coffee v Type II diabetes

http://thechart.blogs.cnn.com/2014/04/24/coffee-may-reduce-risk-for-type-2-diabetes/

Full, free blog from
CNN

How that ingredient in red wine works to benefit health

http://www.biosciencetechnology.com/news/2014/04/secrets-behind-health-benefits-wine-revealed?et_cid=3911360&et_rid=54713780&type=headline

Complete, free essay from
Biosci. Tech.

That stuff is expensive to buy but not to make? Yikes!


http://blogs.scientificamerican.com/observations/2014/04/23/the-quest-84000-sovaldimiracle-cure-costs-less-than-150-to-make/

Full, free article, links from
Sci. Am.

Testing drugs using lab-grown skin

http://www.bbc.com/news/health-27129861

Complete, free report from
BBC News

Blocking myostatin to rebuild muscles

http://online.wsj.com/news/articles/SB10001424052702303978304579475133079434084?mod=dist_smartbrief

Full, free newspaper story, image

Odd drug

Hair pigmentation change with drug


http://www.nejm.org/doi/full/10.1056/NEJMicm1309906?query=TOC

Short, free note, image from
New Engl. j. Med.

New in the pharmaceutical world: April 10-24
Bad drug?
What is in that nutritional supplement you take?

http://blogs.scientificamerican.com/observations/2014/04/02/toxins-in-nutrition-supplements-still-escape-fda-oversight/

Complete, free blog from
Sci. Am.

Children prescribed codeine

http://pediatrics.aappublications.org/content/early/2014/04/16/peds.2013-3171.full.pdf+html

Full, free pdf from
Pediatrics

Your brain on
pot

http://healthyliving.msn.com/health-wellness/study-finds-signs-of-brain-changes-in-pot-smokers

Full, free report from
MSN

How effective is that anti-flu drug?


http://www.dddmag.com/news/2014/04/have-millions-been-wasted-flu-drug?et_cid=3875801&et_rid=54713780&type=headline

Full, free story from Drug discov. & develop.

NSAID's and atrial fibrillation


http://bmjopen.bmj.com/content/4/4/e004059.full

Full, free article, tables, linked citations from BMJ Open

The truth about coffee

Caffeine
v Alzheimer's tau deposits

http://www.biosciencetechnology.com/news/2014/04/caffeine-can-target-tau-deposits-alzheimers?et_cid=3868997&et_rid=54713780&location=top

Complete, free story from Biosci. Tech.

Coffee myths

http://www.nbcnews.com/feature/debunker/perk-evils-coffee-debunked-n17426

Full, free debunking video from MSN

Good drug

Green tea for the brain?

http://www.biosciencetechnology.com/news/2014/04/green-tea-boosts-your-brain?et_cid=3871407&et_rid=54713780&location=top

Full, free essay from Biosci. Tech.

Marijuana for intractable epilepsy

http://www.scientificamerican.com/article/an-ingredient-of-pot-may-help-people-with-epilepsy/?&WT.mc_id=SA_DD_20140422

Complete, free article from Sci. Am.

Georgia governor OK's marijuana trials


http://www.dddmag.com/news/2014/04/governor-backs-medical-marijuana-trials?et_cid=3878080&et_rid=54713780&type=headline

Full, free item from Drug discov. & develop.

Your daily drug discoveries: April 3-10
Toxins in that supplement

http://blogs.scientificamerican.com/observations/2014/04/02/toxins-in-nutrition-supplements-still-escape-fda-oversight/

Complete, free story, links from Sci. Am.

Does vitamin D really reduce mortality?


http://www.bmj.com/content/348/bmj.g2035

Full, free article, graphics, linked citations from BMJ

Immunotherapy for allergies

http://www.dddmag.com/news/2014/04/fda-approves-first-hay-fever-immunotherapy-tablet?et_cid=3860244&et_rid=54713780&type=headline

Short, free item from Drug discov. & develop.

Want information on the new inhalable insulin?

http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM390865.pdf

From the manufacturer

Down on the pharm: March 27-April 3
Product tampering and recall: Alli

http://www.dddmag.com/news/2014/03/tampering-forces-massive-alli-recall?et_cid=3848351&et_rid=54713780&type=headline

Complete, free item from
Drug discov. & develop.

How does aspirin affect mortality in non-surgical cardiac work?

http://www.nejm.org/doi/full/10.1056/NEJMoa1401105?query=OF#t=articleTop

Short, free article, tables, linked citations from New Engl. j. Med.

E-cigarettes not helpful in quitting


http://www.scientificamerican.com/article/electronic-cigarettes-dont-aid-quitting/?&WT.mc_id=SA_DD_20140326

Full, free essay from Sci. Am.

Daily dose of drug data: March 20-27
Fluid for e-cigarettes potentially lethal

http://healthyliving.msn.com/health-wellness/nicotine-e-liquids-a-serious-health-threat-experts

Complete, free item, video from MSN

How does personalized medicine work?

http://www.dddmag.com/videos/2014/03/how-personalized-medicine-works-bananas-and-biomarkers?et_cid=3834351&et_rid=54713780&type=headline

Short note, video from Drug discov. & develop.

Anesthesia's darker side

http://www.scientificamerican.com/article/hidden-dangers-of-going-under/?&WT.mc_id=SA_MB_20140319

Full, free essay from Sci. Am.

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